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Role of er status in the quinquennial overview of randomized adjuvant trials by the early breast cancer trialists collaborative group ebctcg , the use of 5 years of tamoxifen in patients with early-stage breast cancer was associated with a 41 reduction in the annual risk of relapse, and a 34 reduction in the annual death rate for women with er-positive disease, but little benefit was observed for those with er-poor disease.

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If you take tamoxifen for cancer that has spread to the bonesyou may get pain in your bones when you start taking itThis is sometimes called tumour flare.

AThe combination of taking vitamin Da multivitamin and tamoxifen in the morning is not a problemThere are no known drug interactions with these medicationsTaking all three medications at one time may cause stomach upset.

Any sickness usually improves after a few weeksTry taking tamoxifen with food or at night.

Try to cut down on nicotinealcohol and hot drinks containing caffeinesuch as tea and coffeeDress in layersso you can remove clothes as neededWear clothes made from natural fabricssuch as cotton.

To make sure you can safely take tamoxifentell your doctor if you have any of these conditionsLiver disease High cholesterol or triglyceridesa type of fat in the bloodA history of stroke or blood clot A history of cataract If you are receiving chemotherapy or radiation.

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i was told that tamoxifen was just as impt as the chemo.

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